Treatment Type: Diagnostic Procedures
Rated for: Collie (Smooth)
Posted Mar. 27, 2018
ALT is a enzyme which is mainly released when liver cells are damaged.
It is usually interpreted along with other blood results which commonly increase in liver disease: ALP, GGT, total bilirubin, bile acids etc.
Further tests such as blood tests and imaging (x-rays, ultrasound, CT) as well as liver samples (FNA or biopsy) may need to be taken to come to a complete diagnosis.
ALT levels in the blood most commonly increase due to:
1. Infections in the liver
2. Chronic liver disease
4. Medications: phenobarbital (seizure medication), steroids, NSAIDs
5. Reduced blood flow to the liver: heart disease, anaemia
6. Cushing's Disease or Diabetes Mellitus
7. Liver Cancer
8. Toxins: poisonous mushrooms, xylitol etc
The levels of ALT can also increase mildly due to muscle injury or gastrointestinal disease.