Cerenia (maropitant) is the first medication to be US FDA-approved to prevent and treat acute vomiting in dogs and cats. Maropitant is classified as an anti-emetic drug, and works by blocking a neurotransmitter called "Substance P" which stimulates the vomiting reflex. By acting directly at this "vomiting center" in the brain, Cerenia reduces nausea and stops all vomiting, no matter whether it's central (starting in the brain) or peripheral (starting in the stomach) in origin. Cerenia is considered to be the most effective anti-emetic available in veterinary medicine, and is also felt to provide some analgesia (pain-relief) properties.
Cerenia (maropitant) tablets are approved for treating acute vomiting in dogs 7 months and older. Cerenia can also be given in injectable form in the veterinary clinic. Cerenia is proven to be very safe, and produces very few side-effects, with pain at the injection site being the most common problem. Maropitant should be used with caution in dogs who suffer from liver disease as it is mostly metabolized by the liver.
Maropitant has been studied and approved for canine nausea caused by a variety of conditions, including: gastroenteritis, acute pancreatitis, cholangitis, parvovirus, leptospirosis, and motion sickness.
Here is a list of some of the most common canine conditions where Cerenia (maropitant) is used to treat nausea and prevent vomiting.
Vomiting precedes diarrhea in some cases of hemorrhagic gastroenteritis, although rarely. In such cases Cerenia should be used in order to stop the vomiting and limit dehydration, but in a majority of the cases it's not necessary because it doesn't affect diarrhea in any way.
Cerenia is very helpful in reducing the gastrointestinal upset and vomiting associated with Parvovirus. While it doesn't cure the Parvo in any way it will make your pet feel better and possibly allow them to regain their appetite and keep down food which is necessary for recovery. This provides a great deal of comfort to your dog during treatment, while fighting the virus. Cerenia can be given in injectable form in the clinic and sent home as a tablet if they need it. Cerenia works well and has very few side effects. It is fairly cost-effective and definitely worth the money for how well it works.
Cerenia can be used for the prevention of motion sickness, which is particularly important for dogs who suffer from some chronic GI disease like Eosinophilic Gastroenteritis, as motion sickness can lead to exacerbation of the symptoms and acutization of the disease.
Pancreatitis causes nausea and Cerenia is an anti-nausea medication that is very effective in decreasing these symptoms. In many cases of pancreatitis, cerenia can help a dog stop vomiting and start eating earlier in the course of the disease, increasing its chances of survival.
Eosinophilic gastroenteritis is a chronic condition, meaning that it usually manifests with mild symptoms, like occasional vomiting and diarrhea, in which case cerenia isn't really necessary, nor are any other medications for that matter. However almost every chronic disease has periods of acutization, in which symptoms exacerbate and acute vomiting and/or diarrhea can develop. In these cases it's extremely important to stop vomiting as soon as possible, which is where Cerenia can help.
Because Cerenia is an anti-nausea medication that can be given in an injection lasting 24 hours, it can be a great option to get nausea under control for a pet who has been vomiting. The important thing to remember though, is that when Cerenia is used to treat vomiting, it is just masking the clinical signs of the condition, rather than fixing the underlying problem. This is why Cerenia is not indicated in every case with a vomiting dog.
Maropitant is one of the newer anti-nausea veterinary drugs and can be given by injection which is helpful for vomiting patients. It is a once a day treatment which can make things easier for management and there is also a tablet form to help prevent the return of vomiting. There are no significant side effects commonly seen. It takes effect rapidly and works well in most patients.